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Anti-Human CD305 Antibody, clone NKTA255

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti-Human CD305 Antibody, clone NKTA255  ABD12209
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD305
  • FC - Anti-Human CD305 Antibody, clone NKTA255  ABD12209
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD305
  • FC - Anti-Human CD305 Antibody, clone NKTA255  ABD12209
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD305:FITC
  • FC - Anti-Human CD305 Antibody, clone NKTA255  ABD12209
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD305:RPE
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, IP
Primary Accession Q6GTX8
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names NKTA255
Calculated MW 31412 Da
Additional Information
Purification Pack Size: 25 µgPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen NK cell lines B12.100 and AM.25.
Shelf Life 18 months from date of despatch.
Gene ID 3903
Other Names Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1, CD305
Target/Specificity Mouse anti-Human CD305 antibody, clone NKTA255 recognizes human leukocyte-associated Ig-like receptor-1 (LAIR-1), a ~40 kDa cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by non-haematopoietic, platelets or erythrocytes.Mouse anti-Human CD305 antibody, clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules (Poggiet al.1995).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD305 Antibody, clone NKTA255 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Poggi, A. et al. (1995) p40, a novel surface molecule involved in the regulation of the non-major histocompatibility complex-restricted cytolytic activity in humans.
Eur J Immunol. 25 (2): 369-76. 2. Zocchi, M.R. et al. (2001) Leukocyte-associated Ig-like receptor-1 prevents granulocyte-monocyte colony stimulating factor-dependent proliferation and Akt1/PKB alpha activation in primary acute myeloid leukemia cells.
Eur J Immunol. 31 (12): 3667-75. 3. Poggi, A. et al. (2000) Engagement of the leukocyte-associated Ig-like receptor-1 induces programmed cell death and prevents NF-kappaB nuclear translocation in human myeloid leukemias.
Eur J Immunol. 30 (10): 2751-8.

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Cat# ABD12209
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