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Anti-Human KIR Antibody, clone NKVFS1

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti-Human KIR Antibody, clone NKVFS1  ABD12210
    Staining of human peripheral blood lymphocytes with Mouse anti Human KIR: Low Endotoxin
  • FC - Anti-Human KIR Antibody, clone NKVFS1  ABD12210
    Staining of human peripheral blood lymphocytes with Mouse anti Human KIR
  • FC - Anti-Human KIR Antibody, clone NKVFS1  ABD12210
    Staining of human peripheral blood lymphocytes with Mouse anti Human KIR:Azide Free
  • FC - Anti-Human KIR Antibody, clone NKVFS1  ABD12210
    Staining of human peripheral blood lymphocytes with Mouse anti Human KIR
  • FC - Anti-Human KIR Antibody, clone NKVFS1  ABD12210
    Staining of human peripheral blood lymphocytes with Mouse anti Human KIR:RPE
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, E, IP
Primary Accession P43631
Other Accession P43627, P43628, Q14954, P43626, P43632
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names NKVFS1
Calculated MW 33502 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Shelf Life 18 months from date of despatch.
Gene ID 100132285
Other Names Killer cell immunoglobulin-like receptor 2DS2, CD158 antigen-like family member J, MHC class I NK cell receptor, NK receptor 183 ActI, Natural killer-associated transcript 5, NKAT-5, p58 natural killer cell receptor clone CL-49, p58 NK receptor CL-49, CD158j, KIR2DS2, CD158J, NKAT5
Target/Specificity Mouse anti-Human KIR antibody, clone NKVFS1 recognizes KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family, CD158a, CD158b and P50.3. KIR2D family members are cell surface glycoproteins with two Ig domains, which are expressed on natural killer cells and some T cells.Mouse anti-Human KIR antibody, clone NKVFS1 recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4).Mouse anti-Human KIR antibody, clone NKVFS1 is reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms..
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human KIR Antibody, clone NKVFS1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Spaggiari, G. M. et al. (2002) Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8: evidence for a negative regulation exerted by members of the inhibitory receptor superfamily.
Blood. 99: 1706 - 1714. 2. Spaggiari, G. M. et al. (2002) Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction.
Blood: 100: 4098 - 4107. 3. Older Aguilar, A.M. et al. (2010) Coevolution of Killer Cell Ig-Like Receptors with HLA-C To Become the MajorVariable Regulators of Human NK Cells.
J Immunol. 185: 4238-51.

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Cat# ABD12210
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