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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Mouse Lymphotoxin beta Receptor Antibody, clone 5G11b (RPE)   

Anti-Mouse Lymphotoxin beta Receptor Antibody, clone 5G11b

Rat Anti-Mouse Monoclonal Antibody

     
  • FC - Anti-Mouse Lymphotoxin beta Receptor Antibody, clone 5G11b  ABD12211
    Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta
  • FC - Anti-Mouse Lymphotoxin beta Receptor Antibody, clone 5G11b  ABD12211
    Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta : FITC
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC
Primary Accession P50284
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names 5G11b
Calculated MW 44956 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Recombinant extracellular domain of LT beta R.
Shelf Life 18 months from date of despatch.
Gene ID 17000
Other Names Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, Ltbr, Tnfcr, Tnfrsf3
Target/Specificity Rat anti-Mouse Lymphotoxin beta Receptor antibody, clone 5G11b recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Rat anti-Mouse Lymphotoxin beta Receptor antibody, clone 5G11b recognizes surface expressed LT beta R. Rat anti-Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (Hehlganset al.2003).Rat anti-Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is routinely tested on WEH1 cells.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse Lymphotoxin beta Receptor Antibody, clone 5G11b is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Hehlgans, T. et al. (2003) Activation of the lymphotoxin - beta receptor induces NF Kappa B-dependent Interleukin-6 and MIP-2 secretion in mouse fibrosarcoma cells.
Eur. Cytokine Netw. 14: 103 - 107. 2. Palumbo, M.O. et al. (2006) Isolation and characterization of proinsulin-producing medullary thymic epithelial cell clones.
Diabetes. 55: 2595-601. 3. Moore, F. et al. (2007) An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha.
J Immunol. 178: 1301-11. 4. Magari, M. et al. (2011) IL-21-Dependent B Cell Death Driven by Prostaglandin E2, a Product Secreted from Follicular Dendritic Cells.
J Immunol. 187: 4210-8.1. Muller, P. et al. (2001) Functional characterization of the mouse lymphotoxin-beta receptor promoter.
Eur. Cytokine Netw. 12: 325 - 330.

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Cat# ABD12211
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