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Anti-Human CD94 Antibody, clone DX22

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD94 Antibody, clone DX22  ABD12213
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD94
  • FC - Anti-Human CD94 Antibody, clone DX22  ABD12213
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD94 Biotin
  • FC - Anti-Human CD94 Antibody, clone DX22  ABD12213
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD94:FITC
  • FC - Anti-Human CD94 Antibody, clone DX22  ABD12213
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD94:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13241
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names DX22
Calculated MW 20513 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Natural killer cell line.
Shelf Life 12 months from date of reconstitution.
Gene ID 3824
Other Names Natural killer cells antigen CD94, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, CD94, KLRD1, CD94
Target/Specificity Mouse anti-Human CD94 antibody, clone DX22 recognizes human CD94, also known as KLRD1 (Killer cell lectin-like receptor, subfamily D, member 1). CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes.CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes.Mouse anti-Human CD94 antibody, clone DX22 is reported to inhibit the binding of CD94 to HLA-E (Braudet al.1998) and HLA-G (Söderströ al.1997)
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD94 Antibody, clone DX22 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Phillips, J.H. et al. (1996) CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes.
Immunity. 5 (2): 163-72. 2. Braud, V.M. et al. (1998) HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.
Nature. 391 (6669): 795-9. 3. Tomasec, P. et al. (2000) Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.
Science. 287 (5455): 1031. 4. Söderström, K. et al. (1997) CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.
J. Immunol. 159: 1072-5. 5. Hassold, N. et al. (2012) Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib.
Int J Cancer. 131 (6): E916-27. 6. Pianta, S. et al. (2015) Amniotic mesenchymal cells from pre-eclamptic placentae maintain immunomodulatory features as healthy controls.
J Cell Mol Med. Oct 30. [Epub ahead of print]

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Cat# ABD12213
(40 western blots)
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