|Calculated MW||20513 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Natural killer cell line.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Natural killer cells antigen CD94, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, CD94, KLRD1, CD94|
|Target/Specificity||Mouse anti-Human CD94 antibody, clone DX22 recognizes human CD94, also known as KLRD1 (Killer cell lectin-like receptor, subfamily D, member 1). CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes.CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes.Mouse anti-Human CD94 antibody, clone DX22 is reported to inhibit the binding of CD94 to HLA-E (Braudet al.1998) and HLA-G (Söderström.et al.1997)|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD94 Antibody, clone DX22 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Phillips, J.H. et al. (1996) CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes.Immunity. 5 (2): 163-72. 2. Braud, V.M. et al. (1998) HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.Nature. 391 (6669): 795-9. 3. Tomasec, P. et al. (2000) Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.Science. 287 (5455): 1031. 4. Söderström, K. et al. (1997) CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells. J. Immunol. 159: 1072-5. 5. Hassold, N. et al. (2012) Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib.Int J Cancer. 131 (6): E916-27. 6. Pianta, S. et al. (2015) Amniotic mesenchymal cells from pre-eclamptic placentae maintain immunomodulatory features as healthy controls.J Cell Mol Med. Oct 30. [Epub ahead of print]
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