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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human CD205 Antibody, clone MG38 (RPE)   

Anti-Human CD205 Antibody, clone MG38

Mouse Anti-Human Monoclonal Antibody

     
  • IHC - Anti-Human CD205 Antibody, clone MG38  ABD12215
    Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD205 antibody, clone MG38 followed by the Histar detection system . High power
  • IF - Anti-Human CD205 Antibody, clone MG38  ABD12215
    Immunofluorescence staining for a human tonsil cryosection with Mouse anti Human CD205 antibody, clone MG38 , red in A and Mouse anti Human CD21, clone LB21 , green in B. C is the merged image with nuclei counterstained blue using DAPI. Low power
  • IF - Anti-Human CD205 Antibody, clone MG38  ABD12215
    Immunofluorescence staining for a human tonsil cryosection with Mouse anti Human CD205 antibody, clone MG38 , red in A and Mouse anti Human CD21, clone LB21 , green in B. C is the merged image with nuclei counterstained blue using DAPI. Medium power
  • IHC-P - Anti-Human CD205 Antibody, clone MG38  ABD12215
    Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD205 antibody, clone MG38 followed by the Histar detection system . Low power
  • FC - Anti-Human CD205 Antibody, clone MG38  ABD12215
    Staining of KM-H2 cells with Mouse anti Human CD205: FITC
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, FC, IP
Primary Accession O60449
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names MG38
Calculated MW 198311 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen CR-Fn II fusion protein.
Shelf Life 18 months from date of despatch.
Gene ID 100526664;4065
Other Names Lymphocyte antigen 75, Ly-75, C-type lectin domain family 13 member B, DEC-205, gp200-MR6, CD205, LY75, CD205, CLEC13B
Target/Specificity Mouse anti-Human CD205 antibody, clone MG38 recognizes human CD205, a ~205 kDa cell surface glycoprotein that is also known as DEC-205. CD205 is a multilectin receptor which in humans is predominantly expressed by dendritic cells. >Mouse anti-Human CD205 antibody, clone MG38 stains mature monocyte - derived dendritic cells and weakly stains some peripheral blood mononuclear cells. Clone MG38 also stains cortical epithelium in the thymus.Mouse anti-Human CD205 antibody, clone MG38 is routinely tested in flow cytometry on the KM-H2 cell line.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD205 Antibody, clone MG38 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Guo, M. et al. (2000) A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells.
Hum Immunol. 61 (8): 729-38. 2. García-Nieto, S. et al. (2010) Laminin and fibronectin treatment leads to generation of dendritic cells with superior endocytic capacity.
PLoS One. 5(4): e10123. 3. Mikulak, J. et al. (2010) DC-specific ICAM-3-grabbing nonintegrin mediates internalization of HIV-1 into human podocytes.
Am J Physiol Renal Physiol. 299: F664-73. 4. Hatsukari, I. et al (2007) DEC-205-mediated internalization of HIV-1 results in the establishment of silent infection in renal tubular cells.
J Am Soc Nephrol. 18: 780-7. 5. Ebner, S. et al. (2002) A novel role for IL-3: human monocytes cultured in the presence of IL-3 and IL-4 differentiate into dendritic cells that produce less IL-12 and shift Th cell responses toward a Th2 cytokine pattern.
J. Immunol. 168: 6199-6207.1. Kato, M. et al. (2006) Expression of human DEC-205 (CD205) multilectin receptor on leukocytes
Int Immunol 18: 857-69

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Cat# ABD12215
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