|Application ||IHC-F, FC, IP|
|Calculated MW||198311 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||CR-Fn II fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Lymphocyte antigen 75, Ly-75, C-type lectin domain family 13 member B, DEC-205, gp200-MR6, CD205, LY75, CD205, CLEC13B|
|Target/Specificity||Mouse anti-Human CD205 antibody, clone MG38 recognizes human CD205, a ~205 kDa cell surface glycoprotein that is also known as DEC-205. CD205 is a multilectin receptor which in humans is predominantly expressed by dendritic cells. >Mouse anti-Human CD205 antibody, clone MG38 stains mature monocyte - derived dendritic cells and weakly stains some peripheral blood mononuclear cells. Clone MG38 also stains cortical epithelium in the thymus.Mouse anti-Human CD205 antibody, clone MG38 is routinely tested in flow cytometry on the KM-H2 cell line.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD205 Antibody, clone MG38 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Guo, M. et al. (2000) A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells.Hum Immunol. 61 (8): 729-38. 2. García-Nieto, S. et al. (2010) Laminin and fibronectin treatment leads to generation of dendritic cells with superior endocytic capacity.PLoS One. 5(4): e10123. 3. Mikulak, J. et al. (2010) DC-specific ICAM-3-grabbing nonintegrin mediates internalization of HIV-1 into human podocytes.Am J Physiol Renal Physiol. 299: F664-73. 4. Hatsukari, I. et al (2007) DEC-205-mediated internalization of HIV-1 results in the establishment of silent infection in renal tubular cells.J Am Soc Nephrol. 18: 780-7. 5. Ebner, S. et al. (2002) A novel role for IL-3: human monocytes cultured in the presence of IL-3 and IL-4 differentiate into dendritic cells that produce less IL-12 and shift Th cell responses toward a Th2 cytokine pattern.J. Immunol. 168: 6199-6207.1. Kato, M. et al. (2006) Expression of human DEC-205 (CD205) multilectin receptor on leukocytesInt Immunol 18: 857-69
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