|Application ||WB, IHC-F, FC|
|Calculated MW||42445 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Fusion protein mCD147dO-2rCD4d3+4|
|Shelf Life||18 months from date of despatch.|
|Other Names||Basigin, Basic immunoglobulin superfamily, HT7 antigen, Membrane glycoprotein gp42, CD147, Bsg|
|Target/Specificity||Rat anti-Mouse CD147 antibody, clone OX114 recognizes mouse CD147 (also known as basigin). CD147 is a cell surface glycoprotein that is widely expressed on leukocytes, red cells, platelets and endothelial cells. The reported functions of CD147 are diverse and include involvement in T-cell activation, cell adhesion and induction of matrix metalloproteinases.Rat anti-Mouse CD147 antibody, clone OX114 recognizes both isoforms of CD147, the common form containing 2 Ig-like domains and the rare form containing 3 Ig-like domains.Rat anti-Mouse CD147 antibody, clone OX114 is routinely tested in flow cytometry on mouse splenocytes. Note that for staining of whole blood samples increased amounts of antibody may be required due to the presence of CD147 on erythrocytes.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD147 Antibody, clone OX114 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Hanna, S.M. et al. (2003) A novel form of the membrane protein CD147 that contains an extra Ig-like domain and interacts homophilically.BMC Biochemistry 4:17. 2. Agrawal, S.M. et al. (2011) A Novel Regulator of Leukocyte Transmigration into the CNS in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.J Neurosci. 31: 669-77.
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