|Application ||IHC-F, FC, IP|
|Calculated MW||30654 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Transfected COS cells expressing ICAM-2 cDNA|
|Shelf Life||18 months from date of despatch.|
|Other Names||Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2|
|Target/Specificity||Mouse anti-Human CD102 antibody, clone CBRIC2/2 recognizes human CD102, also known as intercellular adhesion molecule-2 (ICAM-2). CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD18 (LFA-1). Reports suggest that the CD102 may play a role in lymphocyte re-circulation and T-cell activation.Mouse anti-Human CD102 antibody, clone CBRIC2/2 is reported to inhibit interactions between CD102 and LFA-1 (De Fougerolles et al.1991).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD102 Antibody, clone CBRIC2/2 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. De Fougerolles, A.R. et al. (1991) Characterization of ICAM-2 and Evidence for a Third Counter-Receptor for LFA-1.J. Exp. Med. 174:253-267. 2. Diacovo, T.G. et al. (1994) A Funtional Integrin Ligand on the Surface of Platelets: Intercellular Adhesion Molecule-2.J. Clin. Invest. 94:1243-1251. 3. Porter, J.C. et al. (2009) Epithelial ICAM-1 and ICAM-2 regulate the egression of human T cells across the bronchial epithelium.FASEB J. 23: 492-502. 4. Banerjee, P. et al. (2007) Human T-cell leukemia virus type 1 (HTLV-1) p12I down-modulates ICAM-1 and -2 and reduces adherence of natural killer cells, thereby protecting HTLV-1-infected primary CD4+ T cells from autologous natural killer cell-mediated cytotoxicity despite the reduction of major histocompatibility complex class I molecules on infected cells.J Virol. 81: 9707-17. 5. Xu. H. et al. (1996) Characterization of murine intercellular adhesion molecule-2.J. Immunol. 156: 4909-14.
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