|Application ||IHC-F, FC|
|Clone Names||9C10 (MFR.4.B)|
|Calculated MW||115696 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Mouse LyD9 haematopoietic progenitor cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, Lymphocyte Peyer patch adhesion molecules subunit alpha, LPAM subunit alpha, VLA-4 subunit alpha, CD49d, Itga4|
|Target/Specificity||Rat anti-Mouse CD49d monoclonal antibody, clone 9C10 recognizes murine alpha 4 integrin (CD49d) also known as VLA-4 subunit alpha, CD49d is a ~150 kDa single pass type I transmembrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1.Clone 9C10 (MFR4.B) is reported to significantly inhibit binding of CD49d to CD106 but only when used in combination with clone R1-2 (Kinashi, T. et al.)|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD49d Antibody, clone 9C10 (MFR.4.B) is for research use only and not for use in diagnostic or therapeutic procedures.|
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