|Application ||FC, IP|
|Clone Names||mIC2/4 (3C4)|
|Calculated MW||31390 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||COS cells transfected with murine ICAM-2|
|Shelf Life||18 months from date of despatch.|
|Other Names||Intercellular adhesion molecule 2, ICAM-2, Lymphocyte function-associated AG-1 counter-receptor, CD102, Icam2, Icam-2|
|Target/Specificity||Rat anti-Mouse CD102 antibody, clone mIC2/4 (3C4) recognizes murine intercellular adhesion molecule-2 (ICAM-2), also known as CD102. Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation.Rat anti-Mouse CD102 antibody, clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1 (Xuet al.1996).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD102 Antibody, clone mIC2/4 (3C4) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Xu, H. et al. (1996) Characterization of murine intercellular adhesion molecule - 2.J. Immunol. 156:4909 - 4914. 2. Soede, R.D. et al. (1999) LFA-1 to LFA-1 signals involve zeta-associated protein-70 (ZAP-70) tyrosine kinase: Relevance for invasion and migration of a T-cell hybridoma.J. Immunol. 163:4253-4261. 3. Jones, D.T. et al. (2013) Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice.Dis Model Mech. 6: 115-24. 4. Xu. H. et al. (1996) Characterization of murine intercellular adhesion molecule-2.J. Immunol. 1996 156: 4909-14.
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