|Application ||IHC-F, FC|
|Clone Names||MFR5 (5H10)|
|Calculated MW||115043 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.|
|Immunogen||Mouse MC/9 cell line|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, Itga5|
|Target/Specificity||Rat anti-Mouse CD49e antibody, clone MFR5 (5H10) recognizes murine integrin alpha 5 (CD49e), which associates with the beta 1 integrin (CD29) to form the fibronectin receptor CD49e/CD29 (VLA-5).VLA-5 plays an important role in cell adhesion and migration and is expressed by mast cells, thymocytes, T-cells and monocytes. Rat anti-Mouse CD49e antibody, clone MFR5 (5H10) has been reported to block CD49e mediated function (Kinashi and Springer 1994).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD49e Antibody, clone MFR5 (5H10) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kinashi, T. and Springer, T. A. (1994) Adhesion Molecules in Hematopoietic cells.Blood cells. 20:25-44. 2. Van der Loo, J. C. M. et al. (1998) VLA-5 Is Expressed by Mouse and Human Long-term Repopulating Hematopoietic Cells and Mediates Adhesion to Extracellular Matrix Protein Fibronectin.J. Clin. Invest. 102:1051-1061. 3. Cukierman, E. et al. (2001) Taking Cell-Matrix adhesions to the Third Dimension.Science. 294:1708-1712 4. Kinashi, T. and Springer, T. (1994) Steel factor and c-kit regulate cell-matrix adhesion.Blood. 83:1033-8.
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