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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Mouse CD49e Antibody, clone MFR5 (5H10) (FITC)   

Anti-Mouse CD49e Antibody, clone MFR5 (5H10)

Rat Anti-Mouse Monoclonal Antibody

     
  • FC - Anti-Mouse CD49e Antibody, clone MFR5 (5H10)  ABD12231
    Staining of mouse peritoneal macrophages with Rat anti Mouse CD49e : Alexa Fluor® 488
  • FC - Anti-Mouse CD49e Antibody, clone MFR5 (5H10)  ABD12231
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD49e: FITC
  • FC - Anti-Mouse CD49e Antibody, clone MFR5 (5H10)  ABD12231
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD49e: FITC
  • FC - Anti-Mouse CD49e Antibody, clone MFR5 (5H10)  ABD12231
    Staining of mouse peritoneal macrophage with Rat anti Mouse CD49e : Alexa Fluor® 647
  • FC - Anti-Mouse CD49e Antibody, clone MFR5 (5H10)  ABD12231
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD49e
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, FC
Primary Accession P11688
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names MFR5 (5H10)
Calculated MW 115043 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Immunogen Mouse MC/9 cell line
Shelf Life 18 months from date of despatch.
Gene ID 16402
Other Names Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, Itga5
Target/Specificity Rat anti-Mouse CD49e antibody, clone MFR5 (5H10) recognizes murine integrin alpha 5 (CD49e), which associates with the beta 1 integrin (CD29) to form the fibronectin receptor CD49e/CD29 (VLA-5).VLA-5 plays an important role in cell adhesion and migration and is expressed by mast cells, thymocytes, T-cells and monocytes. Rat anti-Mouse CD49e antibody, clone MFR5 (5H10) has been reported to block CD49e mediated function (Kinashi and Springer 1994).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD49e Antibody, clone MFR5 (5H10) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Kinashi, T. and Springer, T. A. (1994) Adhesion Molecules in Hematopoietic cells.
Blood cells. 20:25-44. 2. Van der Loo, J. C. M. et al. (1998) VLA-5 Is Expressed by Mouse and Human Long-term Repopulating Hematopoietic Cells and Mediates Adhesion to Extracellular Matrix Protein Fibronectin.
J. Clin. Invest. 102:1051-1061. 3. Cukierman, E. et al. (2001) Taking Cell-Matrix adhesions to the Third Dimension.
Science. 294:1708-1712 4. Kinashi, T. and Springer, T. (1994) Steel factor and c-kit regulate cell-matrix adhesion.
Blood. 83:1033-8.

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Cat# ABD12231
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