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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Mouse CD106 Antibody, clone MVCAM A (429) (RPE)   

Anti-Mouse CD106 Antibody, clone MVCAM A (429)

Rat Anti-Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29533
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names MVCAM A (429)
Calculated MW 81317 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Immunogen Stromal cell line PA6.
Shelf Life 18 months from date of despatch.
Gene ID 22329
Other Names Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, CD106, Vcam1, Vcam-1
Target/Specificity Rat anti-Mouse CD106 antibody, clone MVCAM A (429) recognizes murine vascular adhesion molecule 1 (VCAM-1), a cell surface glycoprotein that is also known as CD106. CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29).Rat anti-Mouse CD106 antibody, clone MVCAM A (429) is reported to partially block VCAM-1 mediated functions (Kinashi and Springer 1994).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD106 Antibody, clone MVCAM A (429) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Kinashi, T. and Springer, T.A. (1994) Adhesion molecules in hematopoietic cells.
Blood Cells. 20:25-44. 2. Wormley, F.L. Jr et al. (2001) Cell adhesion molecule and lymphocyte activation marker expression during experimental vaginal candidiasis.
Infect Immun. 69 (8): 5072-9. 3. Woo, J.M. et al. (2010) Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis.
Arthritis Res Ther. 12(3):R93. 4. Hall, L.J. et al. (2010) Probing local innate immune responses after mucosal immunisation.
J Immune Based Ther Vaccines. 8: 5. 5. Winnik S et al. (2011) Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation.
Eur Heart J. 32 (20): 2573-84. 6. Hamada, T. et al. (2009) Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury.
Am J Pathol. 174: 2265-77. 7. Hamada, T. et al. (2008) Metalloproteinase-9 deficiency protects against hepatic ischemia/reperfusion injury.
Hepatology. 47: 186-98. 8. Baumer, Y. et al. (2011) Telomerase-based immortalization modifies the angiogenic/inflammatory responses of human coronary artery endothelial cells.
Exp Biol Med (Maywood). 236: 692-700. 9. Lau,. H.Y. and Bhatia, M. (2007) Effect of CP-96,345 on the expression of adhesion molecules in acute pancreatitis in mice.
Am J Physiol Gastrointest Liver Physiol. 292: G1283-92.

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Cat# ABD12232
(40 western blots)
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