|Application ||IHC-F, FC|
|Clone Names||MVCAM A (429)|
|Calculated MW||81317 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.|
|Immunogen||Stromal cell line PA6.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, CD106, Vcam1, Vcam-1|
|Target/Specificity||Rat anti-Mouse CD106 antibody, clone MVCAM A (429) recognizes murine vascular adhesion molecule 1 (VCAM-1), a cell surface glycoprotein that is also known as CD106. CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29).Rat anti-Mouse CD106 antibody, clone MVCAM A (429) is reported to partially block VCAM-1 mediated functions (Kinashi and Springer 1994).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD106 Antibody, clone MVCAM A (429) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kinashi, T. and Springer, T.A. (1994) Adhesion molecules in hematopoietic cells.Blood Cells. 20:25-44. 2. Wormley, F.L. Jr et al. (2001) Cell adhesion molecule and lymphocyte activation marker expression during experimental vaginal candidiasis.Infect Immun. 69 (8): 5072-9. 3. Woo, J.M. et al. (2010) Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis.Arthritis Res Ther. 12(3):R93. 4. Hall, L.J. et al. (2010) Probing local innate immune responses after mucosal immunisation.J Immune Based Ther Vaccines. 8: 5. 5. Winnik S et al. (2011) Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation.Eur Heart J. 32 (20): 2573-84. 6. Hamada, T. et al. (2009) Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury.Am J Pathol. 174: 2265-77. 7. Hamada, T. et al. (2008) Metalloproteinase-9 deficiency protects against hepatic ischemia/reperfusion injury.Hepatology. 47: 186-98. 8. Baumer, Y. et al. (2011) Telomerase-based immortalization modifies the angiogenic/inflammatory responses of human coronary artery endothelial cells.Exp Biol Med (Maywood). 236: 692-700. 9. Lau,. H.Y. and Bhatia, M. (2007) Effect of CP-96,345 on the expression of adhesion molecules in acute pancreatitis in mice.Am J Physiol Gastrointest Liver Physiol. 292: G1283-92.
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