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>   home   >   Products   >   Primary Antibodies   >   Anti-Pig SLA Class II DR Antibody, clone 2E9/13    

Anti-Pig SLA Class II DR Antibody, clone 2E9/13 (FITC)

Mouse Anti-Pig Monoclonal Antibody

  • FC - Anti-Pig SLA Class II DR Antibody, clone 2E9/13 (FITC) ABD12239
    Pig peripheral blood lymphocytes stained with Mouse anti Pig SLA Class II DR followed by Goat anti Mouse IgG:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Pig
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names 2E9/13
Additional Information
Other Species B
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Porcine monocytes.
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti-Pig SLA Class II DR antibody, clone 289/13 recognizes SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells.Mouse anti-Pig SLA Class II DR antibody, clone 289/13 reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of porcine SLA DR.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR.Mouse anti-pig SLA class II Dr, clone 2E9/13 immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled porcine peripheral blood mononuclear cells.Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B (Bullidoet al.1997).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin
Storage Store at +4℃ or -20℃.
PrecautionsAnti-Pig SLA Class II DR Antibody, clone 2E9/13 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Bullido, R. et al. (1997) Characterization of five monoclonal antibodies specific for swine class II major histocompatibility antigens and crossreactivity studies with leukocytes of domestic animals.
Dev Comp Immunol. 21 (3): 311-22. 2. Jeong, H.J. et al. (2010) Comparative measurement of cell-mediated immune responses of swine to the Mand N proteins of porcine reproductive and respiratory syndrome virus.
Clin Vaccine Immunol. 17: 503-12. 3. Ding, Q. et al. (2011) Human PD-L1-overexpressing porcine vascular endothelial cells induce functionally suppressive human CD4+CD25hiFoxp3+ Treg cells.
J Leukoc Biol. 90 (1): 77-86.4. Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39: 54.

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Cat# ABD12239
(40 western blots)
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