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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Mouse CD321 Antibody, clone H202-106 (Biotin)   

Anti-Mouse CD321 Antibody, clone H202-106

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti-Mouse CD321 Antibody, clone H202-106  ABD12247
    Staining of mouse peripheral blood platelets with Rat anti Mouse CD321: Biotin
  • FC - Anti-Mouse CD321 Antibody, clone H202-106  ABD12247
    Staining of mouse peripheral blood platelets with Rat anti Mouse CD321
  • FC - Anti-Mouse CD321 Antibody, clone H202-106  ABD12247
    Staining of mouse peripheral blood platelets with Rat anti Mouse CD321
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O88792
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG1
Clone Names H202-106
Calculated MW 32424 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen MTE1/MTE2 stromal cell lines.
Shelf Life 18 months from date of despatch.
Gene ID 16456
Other Names Junctional adhesion molecule A, JAM-A, Junctional adhesion molecule 1, JAM-1, CD321, F11r, Jam1, Jcam, Jcam1
Target/Specificity Rat anti-Mouse CD321 antibody, clone H202-106 recognizes murine CD321, which is also known as junctional adhesion molecule 1 (JAM-1). CD321 is a 32-41kD glycoprotein, which shares similarities with related proteins JAM-2 and JAM-3. CD321 is a multifunctional protein that is primarily expressed by platelets, endothelial and epithelial cells. The CD321 protein co-localises with tight junction molecules in both epithelial and endothelial cells and plays an important role in the regulation of junctional integrity and permeability. In addition, CD321 is a ligand for the integrin LFA-1 and is also involved in the transmigration of leucocytes.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD321 Antibody, clone H202-106 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Malergue, al. (1998) A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets.
Mol. Immunol.35:1111-1119 2. Prestwich, R.J. et al. (2009) Immune-mediated antitumor activity of reovirus is required for therapy and isindependent of direct viral oncolysis and replication.
Clin Cancer Res. 15: 4374-81. 2. Aurrand-Lions, M. et al. (2001) Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members.
Blood.98: 3699-3707. 3. Ebnett, al. (2000) Junctional Adhesion Molecule Interacts with the PDZ Domain-containing Proteins AF-6 and ZO-1.
J. Biol. Chem.275: 27979-27988.

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Cat# ABD12247
(40 western blots)
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