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CD23 Antibody, clone B3B4 (Monoclonal Antibody)

Rat Anti-Mouse Monoclonal Antibody

  • FC - CD23 Antibody, clone B3B4 (Monoclonal Antibody)  ABD12248
    Staining of mouse spleen cells with Rat anti Mouse CD23: Alexa Fluor® 647
  • FC - CD23 Antibody, clone B3B4 (Monoclonal Antibody)  ABD12248
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD23
  • FC - CD23 Antibody, clone B3B4 (Monoclonal Antibody)  ABD12248
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD23: Alexa Fluor® 488
  • FC - CD23 Antibody, clone B3B4 (Monoclonal Antibody)  ABD12248
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD23:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, FC, IP, Func
Primary Accession P20693
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names B3B4
Calculated MW 37648 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Fc epsilon R isolated from the 01.2B2 mouse B cell hybridoma.
Shelf Life 18 months from date of despatch.
Gene ID 14128
Other Names Low affinity immunoglobulin epsilon Fc receptor, Fc-epsilon-RII, Lymphocyte IgE receptor, CD23, Fcer2, Fcer2a
Target/Specificity Rat anti-Mouse CD23 antibody, clone B3B4 recognizes murine CD23, the ~49kDa low affinity Fc receptor for IgE (Fc epsilon RII). In the mouse, CD23 is primarily expressed on mature B lymphocytes and follicular dendritic cells. CD23 is known to play an important role in IgE binding but reports suggest that CD23 may also be involved in B-cell proliferation and differentiation.Rat anti-Mouse CD23 antibody, clone B3B4 is reported to block the binding of IgE to Fc epsilon RII (Rao, M. et al.).
Preservative & Stabilisers Preservative Free
Storage Store at -20℃ only.
PrecautionsCD23 Antibody, clone B3B4 (Monoclonal Antibody) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Rao, M. et al. (1987) Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE.
J. Immunol. 138: 1845 - 1851. 2. Maeda, K. et al. (1992) Murine follicular dendritic cells and low affinity Fc receptors for IgE (Fc epsilonRII).
J. Immunol. 148: 2340 – 2347. 3. Montagnac, G. et al. (2005) Intracellular trafficking of CD23: differential regulation in humans and mice by both extracellular and intracellular exons.
J Immunol. 174: 5562-72 4. Mion, F. et al. (2014) Mast Cells Control the Expansion and Differentiation of IL-10-Competent B Cells.
J Immunol. Sep 29. [Epub ahead of print]

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Cat# ABD12248
(40 western blots)
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