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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human CD50 Antibody, clone MEM-171 (RPE)   

Anti-Human CD50 Antibody, clone MEM-171

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD50 Antibody, clone MEM-171  ABD12249
    Staining of human peripheral blood monocytes with Mouse anti Human CD50
  • FC - Anti-Human CD50 Antibody, clone MEM-171  ABD12249
    Staining of human peripheral blood granulocytes with Mouse anti Human CD50:RPE
  • FC - Anti-Human CD50 Antibody, clone MEM-171  ABD12249
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD50: FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32942
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names MEM-171
Calculated MW 59541 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Human granulocytes
Shelf Life 18 months from date of despatch.
Gene ID 3385
Other Names Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
Target/Specificity Mouse anti-Human CD50 antibody, clone MEM-171 recognizes the human CD50 cell surface glycoprotein, a 110kD molecule also known as ICAM-3.CD50 is a type I transmembrane glycoprotein, containing five immunoglobulin-like C2-type domains, and is a ligand for LFA-1.CD50 is expressed by a wide range of leucocytes. It plays a role in leucocyte adhesion and also acts as a signaling and costimulatory molecule on T lymphocytes.Clone MEM-171 recognizes an epitope in the D2 domain of human CD50 and is reported to partially inhibit CD43 induced apoptosis of TF-1 cells (Cermak, L. et al.2001).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD50 Antibody, clone MEM-171 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Takeuchi, E. et al. (1997) CD50 Worksheet Panel Report.
In Leucocyte Typing VI: White cell differentiation antigens. Edited by Kishimoto, T. et al. Garland Publishing Inc. pp403-406. 2. Cermak, L. et al. (2002) Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules
J. Biol. Chem. 277: 7955-7961.

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Cat# ABD12249
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