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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Mouse CD122 Antibody, clone TM-BETA 1 (FITC)   

Anti-Mouse CD122 Antibody, clone TM-BETA 1

Rat Anti-Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16297
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2b
Clone Names TM-BETA 1
Calculated MW 60539 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Cells from murine IL-2RB+ transformant TART-mBeta.
Shelf Life 18 months from date of despatch.
Gene ID 16185
Other Names Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, CD122, Il2rb
Target/Specificity Rat anti-Mouse CD122 antibody, clone TM-BETA 1 recognizes the murine CD122 cell surface glycoprotein, a ~75-85 kDa molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages.CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells.Rat anti-Mouse CD122 antibody, clone TM-BETA 1 blocks IL-2 high affinity binding to the IL-2R beta receptor (Tanakaet al.1991).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD122 Antibody, clone TM-BETA 1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Tanaka, T. et al. (1991) A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL-4 cells.
J Immunol. 147 (7): 2222-8. 2. Leung, K.T. (2011) The tetraspanin CD9 regulates migration, adhesion, and homing of human cord blood CD34+ hematopoietic stem and progenitor cells.
Blood. 117: 1840-50. 3. Chenoweth, M.J. et al. (2012) IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells.
J Immunol. 188: 4149-57.

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Cat# ABD12250
(40 western blots)
Availability: Inquire
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