Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Mouse CD104 Antibody, clone 346-11A (RPE)   

Anti-Mouse CD104 Antibody, clone 346-11A

Rat Anti-Mouse Monoclonal Antibody

     
  • FC - Anti-Mouse CD104 Antibody, clone 346-11A  ABD12252
    Staining of mouse thymocytes with Rat anti Mouse CD104:Alexa Fluor® 488
  • FC - Anti-Mouse CD104 Antibody, clone 346-11A  ABD12252
    Staining of mouse thymocytes with Rat anti Mouse CD104:Alexa Fluor® 647
  • FC - Anti-Mouse CD104 Antibody, clone 346-11A  ABD12252
    Staining of mouse thymocytes with Rat anti Mouse CD104:Biotin
  • FC - Anti-Mouse CD104 Antibody, clone 346-11A  ABD12252
    Staining of mouse thymocytes with Rat anti Mouse CD104:FITC
  • FC - Anti-Mouse CD104 Antibody, clone 346-11A  ABD12252
    Staining of mouse thymocytes with Rat anti Mouse CD104:RPE
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-F, FC, IP
Primary Accession A2A863
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names 346-11A
Calculated MW 201650 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen TSP-180 purified from Balb/c murine carcinoma.
Shelf Life 18 months from date of despatch.
Gene ID 192897
Other Names Integrin beta-4, CD104, Itgb4
Target/Specificity Rat anti-Mouse CD104 antibody, clone 346-11A recognizes mouse integrin beta 4 (CD104), a 200 kDa glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface. Expression of CD104 is localised to the basal region of a wide variety of epithelial cells. In mice, CD104 is also expressed on peripheral neurones, carcinoma cell lines and a subset of endothelial cells. The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane.Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD104 Antibody, clone 346-11A is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

References

1. Kennel, S.J. et al. (1992) The beta 4 subunit of the integrin family is displayed on a restricted subset of endothelium in mice.
J Cell Sci. 101 ( Pt 1): 145-50. 2. Kennel, S.J. et al. (1989) Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily.
J Biol Chem. 264 (26): 15515-21. 3. Moik, D.V. et al. (2011) Loss of migfilin expression has no overt consequences on murine development and homeostasis.
J Cell Sci. 124: 414-21. 4. Lämmermann, T. et al. (2008) Rapid leukocyte migration by integrin-independent flowing and squeezing.
Nature. 453: 51-5. 5. Sonnenberg, A. et al. (1990) The alpha 6 beta 1 (VLA-6) and alpha 6 beta 4 protein complexes: tissue distribution and biochemical properties.
J Cell Sci. 96:207-17. 6. Kennel, S.J. et al. (1986) Tumor antigen on benign adenomas and on murine lung carcinomas quantitated by a two-site monoclonal antibody assay.
Cancer Res. 46:707-12.

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

Cat# ABD12252
Size:
Quantity:
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Crown Flash17-30% Off
Terms & Conditions