|Calculated MW||41285 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Canine CD34 fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Hematopoietic progenitor cell antigen CD34, CD34, CD34|
|Target/Specificity||Mouse anti-dog CD34 antibody, clone 1H6 is specific for canine homologue of CD34, a glycosylated type 1 transmembrane protein of approximately 110kDa (McSweeneyet al.1998) expressed on the cell suface of endothelial cells and haematopoietic stem cells.Clone 1H6 is a key marker of canine hematopoietic progenitor cells.Clone 1H6 is reported for use in CD34+ enrichment studies, (Goerner, M. et al.2001) and (Horn, P. et al.2004).|
|Preservative & Stabilisers||0.09% Sodium Azide; 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Dog CD34 Antibody, clone 1H6 (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. McSweeney, P.A. et al. (1998) Characterization of monoclonal antibodies that recognize canine CD34.Blood. 91 (6): 1977-86. 2. Goerner, M. et al. (1999) The use of granulocyte colony-stimulating factor during retroviral transduction on fibronectin fragment CH-296 enhances gene transfer into hematopoietic repopulating cells in dogs.Blood. 94 (7): 2287-92. 3. Bhattacharya, V. et al. (2000) Enhanced endothelialization and microvessel formation in polyester grafts seeded with CD34(+) bone marrow cells.Blood. 95 (2): 581-5. 4. Goerner, M. et al. (2001) Sustained multilineage gene persistence and expression in dogs transplanted with CD34(+) marrow cells transduced by RD114-pseudotype oncoretrovirus vectors.Blood. 98 (7): 2065-70. 5. Horn, P.A. et al. (2004) Efficient lentiviral gene transfer to canine repopulating cells using an overnight transduction protocol.Blood. 103 (10): 3710-6. 6. Avallone, G. et al. (2007) The spectrum of canine cutaneous perivascular wall tumors: morphologic, phenotypic and clinical characterization.Vet Pathol. 44 (5): 607-20. 7. Palmieri, C. et al. (2013) Use of electron microscopy to classify canine perivascular wall tumors.Vet Pathol. 50 (2): 226-33. 8. Georges, G. et al. (2001) Engraftment of DLA-haploidentical marrow with ex vivo expanded, retrovirally transduced cytotoxic T lymphocytes.Blood. 98:3447-55.1. McSweeney, P. et al. (1996) Canine CD34: cloning of the cDNA and evaluation of an antiserum to recombinant protein.Blood. 88:1992-2003.
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