|Application ||IHC-F, FC, IP|
|Calculated MW||90834 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||CD62P transfected 300.19 cells.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||P-selectin, CD62 antigen-like family member P, Granule membrane protein 140, GMP-140, Leukocyte-endothelial cell adhesion molecule 3, LECAM3, Platelet activation dependent granule-external membrane protein, PADGEM, CD62P, SELP, GMRP, GRMP|
|Target/Specificity||Mouse anti-Human CD62P antibody, clone Psel.KO.2.12 recognizes the CD62P cell surface antigen, a 140kD glycoprotein also known as P-selectin.CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells (Massagueret al.2000).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD62P Antibody, clone Psel.KO.2.12 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Massaguer, A. et al. (2000) Production and characterization of monoclonal antibodies against conserved epitopes of P-selectin (CD62P).Tissue Antigens. 56 (2): 117-28. 2. Massaguer, A. et al. (2003) Characterization of platelet and soluble-porcine P-selectin (CD62P).Vet Immunol Immunopathol. 96 (3-4): 169-81. 3. Massaguer, A. et al. (2002) Reactivity of CD62P workshop mAbs with resting and activated platelets from different animal species.In: Leucocyte Typing VII. Edited by Mason, D. et al. Oxford University Press, pp 342-343. 4. Major, T.C. et al. (2010) The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer.Biomaterials. 31: 2736-45. 5. Johnson, C.A. Jr. et al. (2008) Flow cytometric assays for quantifying activated ovine platelets.Artif Organs. 32: 136-45. 6. Johnson, C.A. Jr. et al. (2011) Platelet activation in ovines undergoing sham surgery or implant of the second generation PediaFlow pediatric ventricular assist device.Artif Organs. 35 (6): 602-13. 7. Johnson, C.A. Jr. et al. (2011) Biocompatibility assessment of the first generation PediaFlow pediatric ventricular assist device.Artif Organs. 35 (1): 9-21. 8. Dasse, K.A. et al. (2007) Assessment of hydraulic performance and biocompatibility of a MagLev centrifugal pump system designed for pediatric cardiac or cardiopulmonary support.ASAIO J. 53 (6): 771-7. 9. Ding, J. et al. (2015) Quantification of Shear-Induced Platelet Activation: High Shear Stresses for Short Exposure Time.Artif Organs. 39 (7): 576-83. 10. Tran GT et al. (2010) Membrane attack complex of complement is not essential for immune mediated demyelination in experimental autoimmune neuritis.J Neuroimmunol. 229 (1-2): 98-106.
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