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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Mouse CD28 Antibody, clone E18 (RPE)   

Anti-Mouse CD28 Antibody, clone E18

Mouse Anti-Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, Func
Primary Accession P31041
Reactivity Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names E18
Calculated MW 25243 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Alternate immunisation with A20 cells expressing mCD28 and recombinant mCD28Ig.
Shelf Life 18 months from date of despatch.
Gene ID 12487
Other Names T-cell-specific surface glycoprotein CD28, CD28, Cd28
Target/Specificity Mouse anti-Mouse CD28 antibody, clone E18 recognizes murine CD28, a co-stimulatory cell surface molecule expressed by T cell subsets. Clone E18 has been shown to be able to stimulate murine T lymphocytes in combination with anti-mouse CD3.
Preservative & Stabilisers Preservative Free
Storage Store at -20℃ only.
PrecautionsAnti-Mouse CD28 Antibody, clone E18 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Dennehy, K.M. et al. (2006) Cutting edge: monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses.
J Immunol. 176 (10): 5725-9. 2. Beyersdorf, N. et al. (2008) Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody.
Blood. 112 (10): 4328-36. 3. Gogishvili, T. et al. (2012) Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease.
J Allergy Clin Immunol. 130 (6): 1394-403.e4. 4. Pletinckx, K. et al. (2015) Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4.
Eur J Immunol. 45 (2): 480-91.

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Cat# ABD12282
(40 western blots)
Availability: Inquire
Bulk Size
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