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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human EMR3 Antibody, clone 3D7 (RPE)   

Anti-Human EMR3 Antibody, clone 3D7 (FITC)

Hamster Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BY15
Reactivity Human
Host Hamster
Clonality Monoclonal
Isotype IgG
Clone Names 3D7
Calculated MW 72621 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen ARHO-EMR3-CD97 (EGF1) transfectants.
Shelf Life 18 months from date of despatch.
Gene ID 84658
Other Names EGF-like module-containing mucin-like hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha, EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta, EMR3
Target/Specificity Hamster anti-Human EMR3 antibody, clone 3D7 recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin
Storage Store at +4℃ or -20℃.
PrecautionsAnti-Human EMR3 Antibody, clone 3D7 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Matmati, M. et al. (2007) The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes.
J. Leukoc. Biol. 81: 440-448. 2. Drewniak, A. etal. (2009) Changes in gene expression of granulocytes during in vivo granulocyte colony-stimulating factor/dexamethasone mobilization for transfusion purposes.
Blood. 113: 5979-98.1. Stacey, M. et al. (2001) Human epidermal growth factor (EGF) module-containg mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognises a ligand on human macrophages and activated neutrophils.
J. Biol. Chem. 276: 18863-18870.

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Cat# ABD12283
(40 western blots)
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