|Application ||FC, IP|
|Calculated MW||36469 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2, CD23A, CLEC4J, FCE2, IGEBF|
|Target/Specificity||Mouse anti-Human CD23 antibody, clone Bu38 recognizes the human low affinity IgE Fc receptor, CD23, a ~45 kDa that exists in two isoforms CD23a and CD23b, which differ in their cytoplasmic regions. The CD23a molecule is primarily expressed on B-cells. Whereas the CD23b molecule is expressed on activated B-cells and weakly on other haematopoietic cells including a subset of peripheral blood T-cells, natural killer cells, granulocytes and follicular dendritic cells.A soluble ~25-30 kDa form of CD23 also exists. Membrane CD23 is reported to play a role in the down-regulation of IgE production.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD23 Antibody, clone Bu38 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Hellen, E.A. et al. (1991) Immunohistochemical demonstration of CD23 expression on lymphocytes in rheumatoid synovitis.J Clin Pathol. 44 (4): 293-6. 2. Kumar, S. et al. (1996) Use of CD23 (Bu38) on paraffin sections in the diagnosis of small lymphocytic lymphoma and mantle cell lymphoma.Mod Pathol. 9 (9): 925-9. 3. Murray, P.G. et al. (1991) CD23 expression in non-Hodgkin lymphoma: immunohistochemical demonstration using the antibody Bu38 on paraffin sections.J Pathol. 165: 125-8.
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