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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human CD92 Antibody, clone VIM-15b (RPE)   

Anti-Human CD92 Antibody, clone VIM-15b

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WWI5
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names VIM-15b
Calculated MW 73302 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen MV4-11 acute monocyte leukaemia cells.
Shelf Life 18 months from date of despatch.
Gene ID 23446
Other Names Choline transporter-like protein 1, CDw92, Solute carrier family 44 member 1, CD92, SLC44A1, CD92, CDW92, CTL1
Target/Specificity Mouse anti-human CD92 antibody, clone VIM-15b recognizes the C-terminal variant of human CDw92 (isoform 3), also known as CTL1, a 70kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells.CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10 (Wille, S. et al.). Removal of Sodium Azide is recommended prior to use in functional assays. AbD Serotec recommend the use of EQU003 for this purpose.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD92 Antibody, clone VIM-15b is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Wille, S. et al. (2001) Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically in dendritic cells.
J. Immunol. 167: 5795-5804. 2. Majdic, O. et al. (1995) Leucocyte Typing V.
Oxford University Press, Oxford pp.984-985.1. O’Regan, S. et al. (2000) An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.
P.N.A.S. 97: 1835-1840.

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Cat# ABD12298
(40 western blots)
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