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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD61 Antibody, clone Y2/51 (RPE)   

Anti-Human CD61 Antibody, clone Y2/51

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD61 Antibody, clone Y2/51  ABD12309
    Peripheral Human Monocytes stained with Mouse anti Human CD61:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05106
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names Y2/51
Calculated MW 87058 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen PHA stimulated peripheral blood cells.
Shelf Life 12 months from date of reconstitution.
Gene ID 3690
Other Names Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD61, ITGB3, GP3A
Target/Specificity Mouse anti-Human CD61 antibody, clone Y2/51 recognizes CD61, a ~105 kDa glycoprotein, also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51.CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD61 Antibody, clone Y2/51 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Phillips, D.R. et al. (1991) GPIIb-IIIa: the responsive integrin.
Cell 65: 359-362. 2. Hynes, R.O. (1992) Integrins: versatility, modulation, and signaling in cell adhesion.
Cell 69: 11-25. 3. Michelson, A. D. et al. (1995) A panel of platelet mAb for the study of haemostasis and thrombosis in baboons.
Leucocyte Typing V. Oxford University Press p 1230-1231. 4. Gatter, K. et al. (1998) The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.
Histopathology 13:257-267. 5. Kamat, V. et al. (2015) Microfluidic assessment of functional culture-derived platelets in human thrombi under flow.
Exp Hematol. pii: S0301-472X(15)00510-X. 6. Ogino, T. et al. (2014) Erythroid and megakaryocytic differentiation of K562 erythroleukemic cells by monochloramine.
Free Radic Res. 48 (3): 292-302. 7. Tehrani, S. et al. (2010) Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia.
Thromb Res. 126 (3): e225-31. 8. Dircks, B.H. et al. (2012) Platelet-neutrophil aggregate formation in blood samples from dogs with systemic inflammatory disorders.
Am J Vet Res. 73 (7): 939-45. 9. Comazzi, S. et al. (2010) Acute megakaryoblastic leukemia in dogs: a report of three cases and review of the literature.
J Am Anim Hosp Assoc. 46 (5): 327-35. 10. Kamat V et al. (2015) Microfluidic assessment of functional culture-derived platelets in human thrombi under flow.
Exp Hematol. pii: S0301-472X(15)00510-X.

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Cat# ABD12309
(40 western blots)
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