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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human CD273 Antibody, clone MIH14 (RPE)   

Anti-Human CD273 Antibody, clone MIH14

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti-Human CD273 Antibody, clone MIH14  ABD12315
    Staining of human peripheral blood monocytes with Mouse anti Human CD273:Alexa Fluor® 488
  • IHC - Anti-Human CD273 Antibody, clone MIH14  ABD12315
    Immunoperoxidase staining of human tonsil cryosection with Mouse anti Human CD273 antibody, clone MIH14 followed by Histar detection system . High power
  • IHC - Anti-Human CD273 Antibody, clone MIH14  ABD12315
    Immunoperoxidase staining of human tonsil cryosection with Mouse anti Human CD273 antibody, clone MIH14 followed by Histar detection system . High power
  • IHC-P - Anti-Human CD273 Antibody, clone MIH14  ABD12315
    Immunoperoxidase staining of human tonsil cryosection with Mouse anti Human CD273 antibody, clone MIH14 followed by Histar detection system . Medium power
  • FC - Anti-Human CD273 Antibody, clone MIH14  ABD12315
    Staining of human peripheral blood monocytes with Mouse anti Human CD273:RPE
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, FC
Primary Accession Q9BQ51
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names MIH14
Calculated MW 30957 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Human B7-DC transfected L cells.
Shelf Life 18 months from date of despatch.
Gene ID 80380
Other Names Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Target/Specificity Mouse anti-Human CD273 antibody, clone MIH14 detects human CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a ~42 kDa member of the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). CD273 is primarily expressed on dendritic cells, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells.CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD273 Antibody, clone MIH14 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Konishi, J. et al. (2004) B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression.
Clin Cancer Res. 10 (15): 5094-100. 2. Volchenkov, R. et al. (2013) Type 1 regulatory T cells and regulatory B cells induced by tolerogenic dendritic cells.
Scand J Immunol. 77 (4): 246-54.

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Cat# ABD12315
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