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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD276 Antibody, clone MIH42 (RPE)   

Anti-Human CD276 Antibody, clone MIH42

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD276 Antibody, clone MIH42  ABD12317
    Staining of human peripheral blood monocytes with Mouse anti Human CD276:FITC
  • FC - Anti-Human CD276 Antibody, clone MIH42  ABD12317
    Staining of human peripheral blood monocytes with Mouse anti Human CD276:Alexa Fluor® 488
  • FC - Anti-Human CD276 Antibody, clone MIH42  ABD12317
    Staining of human peripheral blood monocytes with Mouse anti Human CD276:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5ZPR3
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names MIH42
Calculated MW 57235 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Shelf Life 18 months from date of despatch.
Gene ID 80381
Other Names CD276 antigen, 4Ig-B7-H3, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, CD276, B7H3
Target/Specificity Mouse anti-Human CD276 antibody, clone MIH42 detects CD276, a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing.CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD276 Antibody, clone MIH42 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Chapoval, A.I. et al. (2001) B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production.
Nat Immunol. 2 (3): 269-74. 2. Sun, X. et al. (2003) Mouse B7-H3 induces antitumor immunity.
Gene Ther. 10 (20): 1728-34. 3. Ma, L. et al. (2007) Complete eradication of hepatocellular carcinomas by combined vasostatin gene therapy and B7H3-mediated immunotherapy.
J Hepatol. 46 (1): 98-106. 4. Tjomsland, V. et al. (2010) Semi mature blood dendritic cells exist in patients with ductal pancreatic adenocarcinoma owing to inflammatory factors released from the tumor.
PLoS One. 5: e13441.

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Cat# ABD12317
(40 western blots)
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