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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human CD50 Antibody, clone Bu65 (FITC)   

Anti-Human CD50 Antibody, clone Bu65

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD50 Antibody, clone Bu65  ABD12319
    Staining of human peripheral blood monocytes with Mouse anti Human CD50
  • FC - Anti-Human CD50 Antibody, clone Bu65  ABD12319
    Staining of human peripheral blood monocytes with Mouse anti Human CD50:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32942
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names Bu65
Calculated MW 59541 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Shelf Life 18 months from date of despatch.
Gene ID 3385
Other Names Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
Target/Specificity Mouse anti-Human CD50 antibody, clone Bu65 recognizes human CD50, also known as Inter-cellular adhesion molecule-3 (ICAM-3). CD50 is an 110kD type I transmembrane glycoprotein which is expressed mainly on resting leukocytes. It interacts with lymphocyte function-associated antigen-1 (LFA-1) and DC-SIGN, and is involved in the intercellular adhesion of leukocytes and augments CD3 signalling in T-lymphocyte activation. CD50 expression induces cancer cell proliferation and over-expression may contribute to cancer progression. It has also been implicated in limiting HIV-1 replication.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD50 Antibody, clone Bu65 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Garland Publishing, Inc. (1998) .
Leucocyte Typing VI. 403–409.1. Biggins, J.E. et al. (2007) ICAM-3 influences human immunodeficiency virus type 1 replication in CD4(+) T cells independent of DC-SIGN-mediated transmission.
Virology. 364: 383-394. 2. Berney, S.M. et al. (1999) ICAM-3 (CD50) cross-linking augments signaling in CD3-activated peripheral human T lymphocytes.
J. Leukoc. Biol. 65: 867-874.3. Kim, Y.G. et al. (2006) ICAM-3-induced cancer cell proliferation through the PI3K/Akt pathway.
Cancer Lett. 239: 103-110.

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Cat# ABD12319
(40 western blots)
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