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Anti-Human CD55 Antibody, clone Bu14

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti-Human CD55 Antibody, clone Bu14  ABD12320
    Staining of human peripheral blood monocytes with Mouse anti Human CD55:FITC
  • FC - Anti-Human CD55 Antibody, clone Bu14  ABD12320
    Staining of human peripheral blood monocytes with Mouse anti Human CD55
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC
Primary Accession P08174
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names Bu14
Calculated MW 41400 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Shelf Life 18 months from date of despatch.
Gene ID 1604
Other Names Complement decay-accelerating factor, CD55, CD55, CR, DAF
Target/Specificity Mouse anti-Human CD55 antibody, clone Bu14 recognizes human CD55, also known as Decay Accelerating Factor (DAF). CD55 is a glycosylphosphatylinositol (GPI) anchored type I surface protein which prevents complement mediated lysis of autologous cells. CD55 functions to limit the formation and accelerate the decay of C3/C5-convertases from the classic and alternative pathway. The molecular weight of CD55 varies between 50 and 100kDa dependent on cell type. Alternative transcripts can lead to soluble DAF, which is detectable in plasma, tears, saliva, urine and cerebrospinal fluid. CD55 is the receptor for CD97, Echovirus and Coxsackie B virus, and has been linked to many diseases including multiple sclerosis, rheumatoid arthritis and cancer development.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD55 Antibody, clone Bu14 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Loveland, B.E. and Szokolai, K. (1998) CD55 Workshop Report NL11
In: Leukocyte Typing VI, Eds Kishmoto, T. et al. Garland publishing . 519-520.1. Ruiz-Arguelles, A. and Llorente, L. (2007) The role of complement regulatory proteins (CD55 and CD59) in the pathogenesis of autoimmune hemocytopenias.
Autoimmun. Rev. 6: 155-161.2. Mikesch, J.H. et al. (2006) Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies.
Biochim. Biophys. Acta. 1766: 42-52.

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Cat# ABD12320
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