|Calculated MW||41400 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Complement decay-accelerating factor, CD55, CD55, CR, DAF|
|Target/Specificity||Mouse anti-Human CD55 antibody, clone Bu14 recognizes human CD55, also known as Decay Accelerating Factor (DAF). CD55 is a glycosylphosphatylinositol (GPI) anchored type I surface protein which prevents complement mediated lysis of autologous cells. CD55 functions to limit the formation and accelerate the decay of C3/C5-convertases from the classic and alternative pathway. The molecular weight of CD55 varies between 50 and 100kDa dependent on cell type. Alternative transcripts can lead to soluble DAF, which is detectable in plasma, tears, saliva, urine and cerebrospinal fluid. CD55 is the receptor for CD97, Echovirus and Coxsackie B virus, and has been linked to many diseases including multiple sclerosis, rheumatoid arthritis and cancer development.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD55 Antibody, clone Bu14 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Loveland, B.E. and Szokolai, K. (1998) CD55 Workshop Report NL11In: Leukocyte Typing VI, Eds Kishmoto, T. et al. Garland publishing . 519-520.1. Ruiz-Arguelles, A. and Llorente, L. (2007) The role of complement regulatory proteins (CD55 and CD59) in the pathogenesis of autoimmune hemocytopenias. Autoimmun. Rev. 6: 155-161.2. Mikesch, J.H. et al. (2006) Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies. Biochim. Biophys. Acta. 1766: 42-52.
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