|Application ||IHC-F, FC|
|Calculated MW||51297 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||BALB/c mouse thymocytes|
|Shelf Life||18 months from date of despatch.|
|Other Names||T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4, Cd4|
|Target/Specificity||Rat anti-Mouse CD4 antibody, clone RM4-5 detects mouse CD4, a 55 kD protein also known as Ly-4 and L3T4. CD4 is a single chain transmembraneous glycoprotein which belongs to the immunoglobulin superfamily, and is primarily expressed on peripheral blood monocytes and tissue macrophages. CD4 is also expressed on a subpopulation of regulatory T cells (CD4+CD25+), which play a key role in the maintenance of self tolerance.Rat anti-Mouse CD4 antibody, clone RM4-5 useful for in vitro blocking of ligand binding, as well as in vitro CD4+ T cell depletions.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD4 Antibody, clone RM4-5 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Fehervari, Z. and Sakaguchi, S. (2004) CD4+ Tregs and immune control. J. Clin. Invest. 114: 1209-1217.
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