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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Anti-Human Annexin V Antibody, clone VAA-33 (FITC)   

Anti-Human Annexin V Antibody, clone VAA-33

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08758
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names VAA-33
Calculated MW 35937 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Recombinant Annexin V
Shelf Life 18 months from date of despatch.
Gene ID 308
Other Names Annexin A5, Anchorin CII, Annexin V, Annexin-5, Calphobindin I, CBP-I, Endonexin II, Lipocortin V, Placental anticoagulant protein 4, PP4, Placental anticoagulant protein I, PAP-I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, VAC-alpha, ANXA5, ANX5, ENX2, PP4
Target/Specificity Mouse anti-Human Annexin V antibody, clone VAA-33 specifically recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). Mouse anti-Human Annexin V antibody, clone VAA-33 has been reported to work in Western blotting applications.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Annexin V Antibody, clone VAA-33 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Gerke, V. and Moss, S.E. (2002) Annexins: From structure to function.
Physiol. Rev. 82: 331-371.

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Cat# ABD12330
(40 western blots)
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