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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti Human Interleukin-4 Antibody    

Anti-Human Interleukin-4 Antibody (Biotin)

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human Interleukin-4 Antibody (Biotin) ABD12333
    Staining of fomalin fixed, paraffin embedded human breast invasive ductal carcinoma with Rabbit anti Human Interleukin-4 following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05112
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 17492 Da
Additional Information
Purification Antisera to human IL-4 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human IL-4
Shelf Life 12 months from date of reconstitution.
Gene ID 3565
Other Names Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra, IL4
Target/Specificity Rabbit anti-Human Interleukin-4 antibody recognizes human IL-4 (Interleukin-4), also known as B-cell stimulatory factor 1, a 129 amino acid pleiotropic cytokine which interacts with multiple cell lineages, including T cells, fibroblasts and haematopoietic cells, and is one of the most important factors involved in B cell IgG1 and IgE class switching.IL-4 signalling through the IL-4 receptor (IL-4R), under the influence of Stat6, induces the differentiation of CD4+ T cells into Th2 helper cells, which themselves then secrete IL-4 along with IL-5, IL-6, IL-10 and IL-13. Excessive secretion of IL-4 by Th2 helper cells has been linked with allergy and elevated IgE levels.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human Interleukin-4 Antibody (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Arai, N. et al. (1989) Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression.
J. Immunol. 142: 274-282.2. Steinke, W. and Borish, L. (2001) Th2 cytokines and asthma. Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists.
Respir. Res. 2: 66-70.

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Cat# ABD12333
(40 western blots)
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