Anti-Mouse CD49d Antibody, clone PS/2 (Biotin)
Rat Anti-Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| FC |
---|---|
Primary Accession | Q00651 |
Reactivity | Mouse |
Host | Rat |
Clonality | Monoclonal |
Isotype | IgG2b |
Clone Names | PS/2 |
Calculated MW | 115696 Da |
Other Species | H |
---|---|
Purification | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
Immunogen | P815 DBA/2 murine mastocytoma cells. |
Shelf Life | 18 months from date of despatch. |
Gene ID | 16401 |
Other Names | Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, Lymphocyte Peyer patch adhesion molecules subunit alpha, LPAM subunit alpha, VLA-4 subunit alpha, CD49d, Itga4 |
Target/Specificity | Rat anti-Mouse CD49d monoclonal antibody, clone PS/2 recognizes murine alpha 4 integrin (CD49d), a ~150kDa single pass type I membrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively (Holzmannet al.1989). CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1 (Sheppardet al.1994).Clone PS/2 has also been reported to block the binding of CD49d to its ligands (Andrewet al.1994). |
Preservative & Stabilisers | 0.09% Sodium Azide; 1% Bovine Serum Albumin |
Storage | Store at +4℃ or at -20 ℃. |
Precautions | Anti-Mouse CD49d Antibody, clone PS/2 (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures. |

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References
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