Anti-Human CD59 Antibody, clone MEM-43/5 (RPE)
Mouse Anti-Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| FC |
---|---|
Primary Accession | P13987 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2b |
Clone Names | MEM-43/5 |
Calculated MW | 14177 Da |
Purification | Purified IgG prepared by affinity chromatography on Protein A |
---|---|
Shelf Life | 18 months from date of despatch. |
Gene ID | 966 |
Other Names | CD59 glycoprotein, 1F5 antigen, 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-inhibitory protein, MAC-IP, MEM43 antigen, Membrane attack complex inhibition factor, MACIF, Membrane inhibitor of reactive lysis, MIRL, Protectin, CD59, CD59, MIC11, MIN1, MIN2, MIN3, MSK21 |
Target/Specificity | Mouse anti-Human CD59 antibody, clone MEM-43/5 reacts with a PI-linked glycoprotein, Mw 18-20kDa found on all types of leucocytes including platelets. The antigen is expressed on many haemopoietic and non-haemopoietic cells. Mouse anti-Human CD59 antibody, clone MEM-43/5 recognizes an epitope distinct to that bound by clone MEM-43. |
Preservative & Stabilisers | 0.09% Sodium azide; Stabilising agent |
Storage | Storage at +4ºC. DO NOT FREEZE. |
Precautions | Anti-Human CD59 Antibody, clone MEM-43/5 (RPE) is for research use only and not for use in diagnostic or therapeutic procedures. |

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References
1. Stefanova, I. et al. (1989) Characterization of a broadly expressed human leucocyte surface antigen MEM-43 anchored in membrane through phosphatidylinositolMol. Immunol. 26: 153-161. 1. Stefanova, I., et al. (1989) in Leucocyte Typing IV: White cell differentiation antigens.Ed. Knapp, W. et al. Oxford University Press pp 678-697. 3. Tandon, N. et al. (1994) Expression and function of multiple regulators of complement activation in autoimmune thyroid disease.Immunology 81: 643-647. 4. Horejsi, V. et al. (1988) Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74).Fol. Bio. (Prague) 34: 23-24. 5. Ellison, B.S. et al. (2007) Complement susceptibility in glutamine deprived breast cancer cells.Cell Div. 2: 20. 6. Vanderplasschen, A. et al. (1998) Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope.Proc Natl Acad Sci U S A. 95: 7544-9. 7. Takemoto, M. et al. (2007) Human herpesvirus 7 infection increases the expression levels of CD46 and CD59 in target cells.J Gen Virol. 88: 1415-22. 8. Ohyama, M. et al. (2006) Characterization and isolation of stem cell-enriched human hair follicle bulge cells.J Clin Invest. 116: 249-60.

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