|Calculated MW||26519 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Mouse CD153/CHO cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor ligand superfamily member 8, CD30 ligand, CD30-L, CD153, Tnfsf8, Cd30l, Cd30lg|
|Target/Specificity||Rat anti-Mouse CD153 antibody, clone RM153 recognizes murine CD153, also known as (CD30 ligand), a 40 kDa type II transmembrane protein belonging to the TNF superfamily.In the mouse CD153 is expressed primarily on activated CD4+ve T cells. The interaction of CD153 with its ligand CD30 is reported to enhance the proliferation of anti-CD3/CD28 co-stimulated T-cells.Clone RM153 is reported to block the functional binding of CD153 and can be used to inhibit the binding of murine CD30 to CD153 (Shimozatoet al.1999).|
|Preservative & Stabilisers||0.09% Sodium Azide; 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD153 Antibody, clone RM153 (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Shimozato, O. et al. (1999) Expression of CD30 ligand (CD153) on murine activated T cells.Biochem Biophys Res Commun. 256 (3): 519-26. 2. Akiba, H. et al. (2000) Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis.J Exp Med. 191: 375-80. 3. Mori, M. et al. (1999) CD30-CD30 ligand interaction in primary cutaneous CD30(+) T-cell lymphomas: A clue to the pathophysiology of clinical regression.Blood. 94: 3077-83.
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