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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD29 Antibody, clone 4B7R (RPE)   

Anti-Human CD29 Antibody, clone 4B7R

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD29 Antibody, clone 4B7R  ABD12353
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD29
  • FC - Anti-Human CD29 Antibody, clone 4B7R  ABD12353
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD29:RPE
  • FC - Anti-Human CD29 Antibody, clone 4B7R  ABD12353
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD29:FITC
  • FC - Anti-Human CD29 Antibody, clone 4B7R  ABD12353
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD29:Biotin
  • FC - Anti-Human CD29 Antibody, clone 4B7R  ABD12353
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD29:Alexa Fluor® 647
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05556
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 4B7R
Calculated MW 88415 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Occular melanoma cell line V+B2.
Shelf Life 18 months from date of despatch.
Gene ID 3688
Other Names Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12
Target/Specificity Mouse anti-Human CD29 monoclonal antibody, clone 4B7R recognizes the human integrin beta 1 subunit, also known as CD29, a ~130 kDa (red) 115 kDa (non-red) single pass type I transmembrane glycoprotein expressed by most leucocytes and mesenchymal stem cells.Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Surface expression of CD29 on human natural killer cells can be reduced by pretreatment with the glutathione-S-transferase inhibitor diethyl maleate (Horvath-Arcidiaconoet al.2003)
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD29 Antibody, clone 4B7R is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Marshall, J.F. et al. (1998) Comparative analysis of integrins in vitroandin vivo in uveal and cutaneous melanomas.
Br J Cancer. 77 (4): 522-9. 2. Pillay, J. et al. (2010) Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia.
J Leukoc Biol. 88: 211-20. 3. Kim, B.S. et al. (2011) Effects of the dichloromethane fraction of dipsaci radix on the osteoblastic differentiation of human alveolar bone marrow-derived mesenchymal stem cells.
Biosci Biotechnol Biochem. 75:13-9. 4. Kato, H. et al. (2012) The primacy of β1 integrin activation in the metastatic cascade.
PLoS One. 7 (10): e46576. 5. Meng, J. et al. (2011) Contribution of human muscle-derived cells to skeletal muscle regeneration in dystrophic host mice.
PLoS One. 6(3):e17454. 6. Horvath-Arcidiacono, J.A. et al. (2003) Human natural killer cell activity against porcine targets: modulation by control of the oxidation-reduction environment and role of adhesion molecule interactions.
Cell Immunol. 222: 35-44. 7. Tan, D.W. et al. (2013) Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells.
Development. 140 (7): 1433-44. 8. Yang, J. et al. (2015) Cordycepin protected against the TNF-a-induced inhibition of osteogenic differentiation of human adipose-derived mesenchymal stem cells.
Int J Immunopathol Pharmacol. 28 (3): 296-307. 9. Gu, Q. et al.(2015)Ginkgo biloba extract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells in a pathway involving Wnt/β-catenin signaling.
Pharmacol Res. 97: 70-8.

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Cat# ABD12353
(40 western blots)
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