|Application ||WB, IHC-P, IHC-F, IF|
|Calculated MW||37986 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Purified porcine surfactant protein D|
|Shelf Life||18 months from date of despatch.|
|Other Names||Pulmonary surfactant-associated protein D, PSP-D, SP-D, Lung surfactant protein D, SFTPD|
|Target/Specificity||ABD12373 detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Pig Surfactant Protein D Antibody, clone 1.7 is for research use only and not for use in diagnostic or therapeutic procedures.|
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