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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   Anti Human BAX (N-Terminal) Antibody, clone 2D2    

Anti Human BAX (N-Terminal) Antibody, clone 2D2

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q07812
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2D2
Calculated MW 21184 Da
Additional Information
Other Species M,African Green Monkey ,B
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen A synthetic peptide corresponding to the N-terminal region (aa 3-16) of human Bax having the sequence C-GSGEQPRGGGPTSS.
Shelf Life 18 months from date of despatch.
Gene ID 581
Other Names Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4
Target/Specificity Mouse anti Human BAX antibody, clone 2D2 recognizes an epitope within the N-terminal (NT) region of human apoptosis regulator BAX, also known as Bcl-2-like protein 4. BAX is a pro-apoptotic member of the Bcl-2 family. BAX accelerates programmed cell death by binding to and antagonizing the apoptosis repressor Bcl-2 or its adenovirus homolog E1B 19k protein. It also induces the release of cytochrome C , activation of caspase-3 and thereby apoptosis. Defects in BAX are found in some cell lines from hematopoietic malignancies as T-cell acute lymphoblastic leukemia, Burkitt lymphoma, and plasmacytoma (Brimmellet al.1998).Mouse anti Human BAX antibody, clone 2D2 has been successfully used for the immunoprecipitation of bovine BAX from thymus (Basañezet al.1999).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human BAX (N-Terminal) Antibody, clone 2D2 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12379
(40 western blots)
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