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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Human Cytochrome C Antibody, clone 2G8    

Anti Human Cytochrome C Antibody, clone 2G8

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P99999
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2G8
Calculated MW 11749 Da
Additional Information
Other Species Rb,M,Rat
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Human cytochrome c
Shelf Life 18 months from date of despatch.
Gene ID 54205
Other Names Cytochrome c, CYCS, CYC
Target/Specificity ABD12382 recognises cytochrome c, originally termed Apaf-2, an evolutionarily conserved protein which acts as an essential mitochondrial electron carrier between respirable substrates and oxygen, during aerobic energy production. A second major function for cytochrome c is its role as an intermediate in apoptosis, both through its association with inositol-3-phosphate receptor (IP3 receptor) which acts as an ER calcium release channel, and its association with apoptotic protease activating factor 1 (Apaf-1), resulting in the formation of the apoptosome protein complex which then recruits and activates pro-caspase 9 (Apaf-3). Clone 2G8 is reported to block the role of cytochrome c as a co-factor in the activation of caspase 9. Removal of sodium azide is recommended prior to use in functional assays – AbD Serotec recommend the use of EQU003 for this purpose.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human Cytochrome C Antibody, clone 2G8 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12382
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
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