Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   Anti Human LMO2 Antibody, clone 1A9-1    

Anti Human LMO2 Antibody, clone 1A9-1

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25791
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 1A9-1
Calculated MW 18358 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Purified GST-LMO2 fusion protein.
Shelf Life 18 months from date of despatch.
Gene ID 4005
Other Names Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, T-cell translocation protein 2, LMO2, RBTN2, RBTNL1, RHOM2, TTG2
Target/Specificity Mouse anti Human LMO2 antibody, clone 1A9-1 recognizes the human Rhombotin-2 also known as LMO2 or T-cell translocation protein 2. LMO2 is a 158 amino acid ~24kD transcription factor containing 2 LIM domains that interacts with DNA binding proteins such as TAL1/SCLandGATA1. In early development, LMO2 is expressed in the central nervous system (Herberthet al.2005) and a wide range of tissue, and in adults in myeloid and erythroid precursors, in normal germinal centre B-cells, endothelial cells and parts of the brain (Natkunamet al.2006). LMO2 plays a vital role in early stages of haematopoiesis and in regulating yolk-sac erythropoiesis in mice (Kathleenet al.2005). Studies suggest that it may also play a role in angiogenesis (Yamadaet al.2002).A major cause of T-cell acute lymphoblastic leukemia (T-ALL) is the aberrant activation of the TAL1/SCL, LMO1/2, and NOTCH1 oncogenes (Ferrandoet al.2004). Activation of the Notch signalling pathway by mutations in either the gamma-secretase or PEST domains are found in more than 50% of all T-ALL, including LMO2-induced T-ALL, and studies using mouse models, have show that activation of Notch co-operates with Scl/Lmo1 in inducing T-ALL (Wenget al.2004). Aberrant expression of LMO2 has also been linked to certain types of B-cell lymphoma (Natkunamet al.2008) and prostate cancer, with overexpression possibly linked to cancer progression (Maet al.2007).Mouse anti human LMO2, clone 1A9-1 has been used for the detection of LMO2 by immunohistochemistry on formalin fixed, paraffin embedded tissues and by Western blotting (Natkunamet al.2006).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human LMO2 Antibody, clone 1A9-1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# ABD12385
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions