|Application ||WB, E|
|Other Accession||P02679, P02675|
|Calculated MW||94973 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Fibrin degradation products|
|Shelf Life||18 months from date of despatch.|
|Other Names||Fibrinogen alpha chain, Fibrinopeptide A, Fibrinogen alpha chain, FGA|
|Target/Specificity||Mouse anti Human Fibrinogen antibody, clone 40F11 recognizes human fibrinogen, a glycoprotein produced in the liver. Fibrinogen is a hexamer, consisting of two sets of three subunits (alpha, beta and gamma). Thrombin converts fibrinogen into fibrin, which is then cross-linked by factor XIII to form a blood clot. Mouse anti Human Fibrinogen antibody, clone 40F11 also recognizes fibrin degradation products (FDPs), substances that are left behind after a blood clot dissolves. This process, called fibrinolysis, is produced by the action of enzymes such as plasmin on fibrin. One FDP is D-dimer, levels of which can be used to diagnose deep vein thrombosis or pulmonary embolism. The fibrinolytic system is also closely linked to the control of inflammation.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Fibrinogen Antibody, clone 40F11 is for research use only and not for use in diagnostic or therapeutic procedures.|
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