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>   home   >   Products   >   Primary Antibodies   >   Anti Human S100 Protein Alpha/Beta Antibody, clone 3B10    

Anti Human S100 Protein Alpha/Beta Antibody, clone 3B10

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 3B10
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Human brain S100 protein
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti Human S100 Protein alpha/beta antibody, clone 3B10 recognizes S100 protein derived from human brain tissue. It is a 21kDa acidic calcium-binding protein synthesised by astroglial cells. It can be found predominantly as two isoforms, the alpha-beta heterodimer (S100a) and the beta-beta homodimer (S100b). The S-100 family of proteins have been implicated in a large variety of intracellular and extracellular regulatory activities, such as cellular energy metabolism, cytoskeleton modification, cell proliferation and differentiation. When glial cells are damaged, S100 protein is leaked into the extracellular matrix and cerebrospinal fluid, further releasing into the bloodstream. S100 protein can be used as a sensitive and reliable marker for nervous system damage, such as after brain damage or acute stroke. Mouse anti Human S100 Protein alpha/beta antibody, clone 3B10 recognizes S100a (the alpha-beta heterodimer). Mouse anti Human S100 Protein alpha/beta antibody, clone 3B10 is sensitive to EDTA and other bivalent-binding agents. Improved performance can be obtained in the presence of 5mM CaCl2 in assay buffers.
Preservative & Stabilisers 0.09%Sodium Azide
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human S100 Protein Alpha/Beta Antibody, clone 3B10 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12407
(40 western blots)
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