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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Anti Mouse Interleukin-6 Antibody, clone 6B4 IGH 54    

Anti Mouse Interleukin-6 Antibody, clone 6B4 IGH 54

Rat Anti-Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E, Func
Primary Accession P08505
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG1
Clone Names 6B4 IGH 54
Calculated MW 24384 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Natural partially purified mouse IL-6.
Shelf Life 18 months from date of despatch.
Gene ID 16193
Other Names Interleukin-6, IL-6, B-cell hybridoma growth factor, Interleukin HP-1, Il6, Il-6
Target/Specificity Rat anti Mouse Interleukin-6 antibody, clone 6B4 IGH 54recognizes mouse IL-6 (interleukin-6), a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts acts as the primary inducer of the acute phase response in the liver.IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130). IL-6 can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue.Rat anti Mouse Interleukin-6 antibody, clone 6B4 IGH 54 can be used to neutralize the activity of 50pg/ml of recombinant mouse IL-6 by >95% in a functional assay.
Preservative & Stabilisers None present
Storage Store at -20℃ only.
PrecautionsAnti Mouse Interleukin-6 Antibody, clone 6B4 IGH 54 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12415
(40 western blots)
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