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Anti Ebola Virus Antibody, clone FE18

Mouse Anti-Viral Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q05128
Other Accession Q2PDK5, Q77DJ6
Reactivity Virus
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names FE18
Calculated MW 35183 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Purified inactivated Ebola virus (Zaire strain).
Shelf Life 18 months from date of despatch.
Gene ID 911825
Other Names Matrix protein VP40, Membrane-associated protein VP40, VP40
Target/Specificity Mouse anti Ebola Virus antibody, clone FE18 recognizes the VP40 matrix protein of the Zaire strain of the Ebola virus, a virus that causes hemorrhagic fever. Ebola hemorrhagic fever is potentially lethal and is characterised by a wide range of symptoms including fever, vomiting, diarrhea, generalized pain or malaise, and sometimes internal and external bleeding. The cause of death is usually hypovolemic shock or organ failure. Mortality rates are extremely high, the Zaire strain of the Ebola virus is the most lethal (up to 90% mortality rate). The viruses are characterised by a long, filamentous morphology surrounded by a protein/lipid viral envelope and are transmitted by direct contact with infected blood, body fluids or tissues.VP40 promotes viral assembly and budding by interacting with host proteins of the multivesicular body pathway. It may exist as a monomer, homo-hexamer or homo-octamer.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Ebola Virus Antibody, clone FE18 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12422
(40 western blots)
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