|Calculated MW||30819 Da|
|Other Species||Cynomolgus monkey,Rh|
|Purification||Purified IgG prepared by affinity chromatography|
|Shelf Life||6 months from date of despatch.|
|Other Names||Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25, IL2RA|
|Target/Specificity||Mouse anti Human CD25 antibody, clone BC96 recognizes the human CD25 cell surface antigen, also known as the Interleukin-2 receptor subunit alpha or TAC antigen. CD25 is derived from a 272 amino acid precursor to yield a 251 amino acid monomeric receptor of ~53kDa which acts as the low affinity receptor for IL-2. CD25 can also form a heterodimer with CD122 to form the high affinity receptor for IL-2. CD25 is expressed by activated lymphocytes (Jacksonet al.1990,Butcheret al.1990). Defects in CD4+/ CD25+ reglatory T cells have been implicated in the pathogenesis of autoimmune diabetes (Lindleyet al.2005) and other autoimmune conditions (Sakaguchiet al.1995).|
|Preservative & Stabilisers||0.09% Sodium Azide, 0.2% Bovine Serum Albumin|
|Storage||Store at +4℃.DO NOT FREEZE.|
|Precautions||Anti Human CD25:RPE-Cy5 Antibody, clone BC96 is for research use only and not for use in diagnostic or therapeutic procedures.|
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