|Calculated MW||147254 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Shelf Life||6 months from date of despatch.|
|Other Names||Receptor-type tyrosine-protein phosphatase C, 188.8.131.52, Leukocyte common antigen, L-CA, T200, CD45, PTPRC, CD45|
|Target/Specificity||Mouse anti Human CD45RA antibody, clone HI100 recognises the human CD45RA cell surface antigen, the 220 kDa exon 4 splice variant of the leucocyte common antigen, also known as CD45, LCA or Receptor-type tyrosine-protein phosphatase C. CD45 is a single pass type I transmembrane glycoprotein with two fibronectin type III domains and two tyrosine-protein phosphatase domains (UniProt: P08575). CD45RA is expressed by a subset of T lymphocytes, B lymphocytes and most monocytes.Mutations in the CD45 gene can lead to sever combined immunodeficiency disease characterised by a complete lack of the T cell mediated immune response (Tchilianet al.2001) and a susceptibility for the development of multiple sclerosos (Jacobsenet al.2000).|
|Preservative & Stabilisers||0.09% Sodium Azide, 0.2% Bovine Serum Albumin|
|Storage||Store at +4℃.DO NOT FREEZE.|
|Precautions||Anti Human CD45RA:RPE-Cy5 Antibody, clone HI100 is for research use only and not for use in diagnostic or therapeutic procedures.|
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