|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Glycoprotein haemagglutinin-neuraminidase of Newcastle Disease Virus (La-Sota strain).|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti Newcastle Disease Virus antibody, clone 8H2 recognizes the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV). Newcastle disease is a highly contagious disease affecting wild and domestic birds.Symptoms of the disease vary greatly, depending on the strain of virus and the species, age and health of the bird. Virulence of the disease can also vary greatly, with some strains causing very high mortality rates. In humans, NDV can cause mild influenza-like symptoms. The HN protein of the virus is a type II membrane glycoprotein on virion and infected cell surfaces. It binds to sialic acid-containing cellular receptors and promotes activity of the viral fusion protein, thereby allowing the virus to penetrate the cell. It also removes sialic acids from progeny virus particles to prevent viral self-agglutination. Newcastle disease virus is tumor selective and oncolytic. It has shown promise for selective growth in and killing of a variety of tumor cells.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Newcastle Disease Virus Antibody, clone 8H2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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