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>   home   >   Products   >   Primary Antibodies   >   Anti Plasmodium vivax CSP Antibody, clone PVC-1    

Anti Plasmodium vivax CSP Antibody, clone PVC-1

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names PVC-1
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti Plasmodium vivax CSP antibody, clone PVC-1 recognizes the circumsporozoite protein (CSP) of Plasmodium vivax. Outside sub-Saharan Africa, where P. falciparum infection is most common, P. vivax is the most common cause of malaria infection. While not as deadly as P. falciparum, it does negatively affect human health. Malaria infection is initiated when an infected Anopheles mosquito injects sporozoites into a person’s blood during a blood meal. The sporozoites migrate to and infect hepatocytes where they multiply asexually. The CSP is the major surface protein of sporozoites and form a dense coat on the parasite’s surface. The CSP is involved in the motility of the sporozoite and the invasion of target cells. It is also required for sporozoite development in the mosquito. The protein has been extensively studied as a vaccine candidate. Vaccination with irradiated sporozoites has been shown to protect against malarial parasites with the sera of protected individuals recognising CSP.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Plasmodium vivax CSP Antibody, clone PVC-1 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12442
(40 western blots)
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