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>   home   >   Products   >   Primary Antibodies   >   Anti Rat C-Peptide I Antibody, clone 6H1    

Anti Rat C-Peptide I Antibody, clone 6H1

Mouse Anti-Rat Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01322
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 6H1
Calculated MW 12421 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Fragments of rat C-peptide conjugated to a carrier protein.
Shelf Life 18 months from date of despatch.
Gene ID 24505
Other Names Insulin-1, Insulin-1 B chain, Insulin-1 A chain, Ins1, Ins-1
Target/Specificity Mouse anti Rat C-Peptide I antibody, clone 6H1 recognizes rat C-peptide I. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Mouse anti Rat C-Peptide I antibody, clone 6H1 recognizes rat C-peptide I and rat proinsulin. It does not recognize mouse C-peptide I and reacts very weakly with rat and mouse C-peptide II.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Rat C-Peptide I Antibody, clone 6H1 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12469
(40 western blots)
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