|Calculated MW||24847 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Purified recombinant human growth hormone.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Somatotropin, Growth hormone, GH, GH-N, Growth hormone 1, Pituitary growth hormone, GH1|
|Target/Specificity||Mouse anti Human Growth Hormone antibody, clone GhB9 recognizes human growth hormone (hGH), a 22 kDa polypeptide synthesised by acidophilic or somatotropic cells of the anterior pituitary gland. It is also referred to as somatotropin. Many different isoforms exist in humans, from monomers to pentamers, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Human GH binds to two GH receptors and induces signal transduction through receptor dimerisation. Growth hormone plays an important role in growth and cell production. An excess of GH results in acromegaly or gigantism, characterised by excessive growth. It can also be accompanied by muscle weakness, insulin resistance and pressure on nerves. Deficiency of GH may result in lack of strength, energy and bone mass. Growth hormone can be used to treat conditions that result in short stature or decreased muscle mass.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Growth Hormone Antibody, clone GhB9 is for research use only and not for use in diagnostic or therapeutic procedures.|
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