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>   home   >   Products   >   Primary Antibodies   >   Anti Rat CD80 Antibody, clone 3H5    

Anti Rat CD80 Antibody, clone 3H5

Mouse Anti-Rat Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3H5
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen HTLV-1 transformed Lewis-S1 cells.
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti Rat CD80, clone 3H5 specifically recognizes rat CD80, otherwise known as B7-1, a type I transmembrane glycoprotein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells. CD80 is a B cell activation antigen, which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation and proliferation. In contrast, the interaction of CD80 with CD152 has an inhibitory effect on T cell responses. Clone 3H5 has been shown to block the co-stimulatory activity of rat CD80.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Rat CD80 Antibody, clone 3H5 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12482
(40 western blots)
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